Author(s): Lahm GP, Stevenson TM, Selby TP, Freudenberger JH, Cordova D,
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Abstract Rynaxypyr is a highly potent and selective activator of insect ryanodine receptors with exceptional activity on a broad range of Lepidoptera. A strong correlation between insecticidal activity and ryanodine receptor activation is observed along with selective activity against insect over mammalian receptors. The synthesis and biological results are presented.
This article was published in Bioorg Med Chem Lett
and referenced in Journal of Physical Chemistry & Biophysics