alexa Safety and hypoglycaemic properties of aqueous leaf extract of Ocimum gratissimum in streptozotocin induced diabetic rats.
Pharmaceutical Sciences

Pharmaceutical Sciences

Medicinal & Aromatic Plants

Author(s): Egesie UG, Adelaiye AB, Ibu JO, Egesie OJ

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Abstract The claim by Nigerian traditional herbal medicine practitioners that Ocimum gratissimum leaves has antidiabetic properties was investigated. Diabetes mellitus was induced with streptozotocin and graded doses of the aqueous leaf extract were administered orally to the experimentally diabetic rats for 28 days. Administration of the aqueous leaf extract caused a statistically significant reduction in plasma glucose level in streptozotocin induced diabetic rats. The extract appeared nontoxic as evidenced by normal serum levels of AST, ALT, ALP, TPT, ALB and bilirubin. These data appear to agree with claimed hypoglycaemic effects of Ocimum gratissimum.
This article was published in Niger J Physiol Sci and referenced in Medicinal & Aromatic Plants

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