alexa Saliva composition and functions: a comprehensive review.
Bioinformatics & Systems Biology

Bioinformatics & Systems Biology

Metabolomics:Open Access

Author(s): de Almeida Pdel V, Grgio AM, Machado MA, de Lima AA, Azevedo LR

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Abstract AIM: The aim of this study was to perform a literature review about the composition and functions of saliva as well as describe the factors that influence salivary flow (SF) and its biochemical composition. BACKGROUND: Saliva represents an increasingly useful auxiliary means of diagnosis. Sialometry and sialochemistry are used to diagnose systemic illnesses, monitoring general health, and as an indicator of risk for diseases creating a close relation between oral and systemic health. REVIEW: This review provides fundamental information about the salivary system in terms of normal values for SF and composition and a comprehensive review of the factors that affect this important system. CONCLUSION: Since several factors can influence salivary secretion and composition, a strictly standardized collection must be made so the above-mentioned exams are able to reflect the real functioning of the salivary glands and serve as efficient means for monitoring health. CLINICAL SIGNIFICANCE: Since many oral and systemic conditions manifest themselves as changes in the flow and composition of saliva the dental practitioner is advised to remain up-to-date with the current literature on the subject.
This article was published in J Contemp Dent Pract and referenced in Metabolomics:Open Access

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