alexa Salvage radical prostatectomy after radiation therapy and brachytherapy.


Journal of Nuclear Medicine & Radiation Therapy

Author(s): Russo P

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Abstract Local recurrence after any type of radiation therapy presents the clinician with a significant challenge. If there is no evidence of metastatic disease, patients can be offered a potentially curative salvage prostatectomy. To qualify for such surgery, patients should be at least 12 months from the completion of radiation and have at least a 10-year life expectancy; ideally, they will have a serum prostate specific antigen concentration <10 ng/mL and a Gleason score of 7 or less. Perioperative complications are substantial, with urinary incontinence rates of 40\% to 50\% and rectal injury rates of 10\% to 15\%. Long-term disease-free survival rates of 30\% to 40\% can be expected. This article was published in J Endourol and referenced in Journal of Nuclear Medicine & Radiation Therapy

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