alexa Sarcomas in north west England: I. Histopathological peer review.


Journal of Cancer Science & Therapy

Author(s): Harris M, Hartley AL, Blair V, Birch JM, Banerjee SS,

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Abstract A total of 468 cases of bone, soft tissue and visceral sarcomas (and certain other tumours) diagnosed during the years 1982-84 in North West England were entered in a study of histopathological peer review, incidence and survival. This paper describes the effects of peer review. Material was reviewed by a panel of five pathologists for 413 of the 450 cases originally registered as sarcomas with the Regional Cancer Registry. The diagnosis of sarcomas was confirmed in 76\% cases and and there was agreement on sub-type for 53\% cases. Measures of agreement were lowest for the two sub-types most commonly diagnosed i.e. malignant fibrous histiocytoma and leiomyosarcoma. Degree of agreement between individual pathologists and final panel diagnosis was also very variable but never less than 65\%. It is concluded that second opinion is essential in cases of presumed sarcomas for studies of incidence and aetiology and to ensure that appropriate treatment is selected.
This article was published in Br J Cancer and referenced in Journal of Cancer Science & Therapy

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