alexa Scaling properties of coding and non-coding DNA sequences
Bioinformatics & Systems Biology

Bioinformatics & Systems Biology

Journal of Theoretical and Computational Science

Author(s): A Provata, Y Almirantis

Abstract Share this page

We study the size distribution of purine and pyrimidine clusters in coding and non-coding DNA sequences. We observe that the cluster-size distribution P(s) follows an exponential decay in coding sequences whereas it follows a power-law decay in non-coding sequences: P(s) ∼ s−1−μ, with a power exponent μ = 1.5–1.8. The mean-square displacement σ2(m) is examined via a cluster walk model, with step-size distribution following P(s) and with m denoting the number of clusters covered by the walker. The behaviour of the mean-square displacement is σ2(m) ∼ m2/μ for non-coding sequences and σ2(m) ∼ m for coding sequences. We associate the power-law behaviour in the non-coding with the tendency of large Pu and Py cluster formation which dominate the non-coding. Under this observation the entire DNA sequence may be regarded as a collection of extended non-coding regions interrupted by small coding regions. We recall that this irregular composition of DNA, is of vital importance for the living organisms: Transposable elements and other “parasite” DNA which try to incorporate themselves into the DNA chain most probably intersect the large non-coding regions, thus leaving the organism unaffected, as is well known to biologists

This article was published in EconPapers and referenced in Journal of Theoretical and Computational Science

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Relevant Topics

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version