alexa Sclerosing inflammatory myofibroblastic tumour of the tongue: an immunohistochemical and ultrastructural study.


Oral Health Case Reports

Author(s): Ide F, Shimoyama T, Horie N, Ide F, Shimoyama T, Horie N

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Abstract A case of inflammatory myofibroblastic tumour (IMT) arising in the tongue of a 27-year-old man is described. The patient presented with a solitary, well-circumscribed submucosal mass of 4 months duration. The tumour showed in its largest part a paucicellular sclerosing lesion resembling a hyalinizing granuloma surrounded by a thin rim of an admixture of myofibroblasts, plasma cells and foamy histiocytes. Myofibroblasts expressed vimentin and alpha-smooth muscle actin positive immunophenotypes. Ultrastructurally the hyaline areas were composed of abundant collagen fibres with sparse myofibroblasts. Extensive scar-like change in this IMT may be related to a traumatic insult.
This article was published in Oral Oncol and referenced in Oral Health Case Reports

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