alexa Sclerosing mesenteritis. Response to cyclophosphamide.
Clinical Research

Clinical Research

Journal of Clinical Case Reports

Author(s): Bush RW, Hammar SP Jr, Rudolph RH

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Abstract We present two patients with an aggressive form of sclerosing mesenteritis characterized by a progressive, life-threatening course, prominent retroperitoneal disease, and tubuloreticular structures in one case, an ultrastructural feature associated with autoimmune and cyclophosphamide-responsive diseases. In both patients, aggressive immunosuppressive medical therapy with cyclophosphamide resulted in prompt, dramatic improvement, without recurrence. When the diagnosis of sclerosing mesenteritis is established, we recommend early aggressive medical therapy with cyclophosphamide, particularly when tubuloreticular structures are present.
This article was published in Arch Intern Med and referenced in Journal of Clinical Case Reports

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