Author(s): Akslen LA, Glattre E, Akslen LA, Glattre E
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Abstract In a population-based survey of 3658 thyroid cancer patients diagnosed in Norway during 1955-85, a total of 200 cases of second malignancies were observed (30,414 person-years, mean follow-up 8.4 years). Male patients had a significantly increased incidence of urogenital cancer [standardised incidence ratio (SIR) = 1.96, 95\% confidence interval (CI) 1.4-2.7], including cancer of the testis (SIR = 11.8, 95\% CI 3.2-30.1) and urinary bladder (SIR = 3.0, 95\% CI 1.5-5.2). The occurrence of malignant melanoma was also increased among males (SIR = 4.2, 95\% CI 1.4-9.7). This apparent association with urogenital cancers among males at the present time cannot be explained, although increased surveillance as well as specific aetiological factors should be considered.
This article was published in Eur J Cancer
and referenced in Journal of Clinical & Experimental Dermatology Research