alexa Second-line drug susceptibilities of Thai multidrug-resistant Mycobacterium tuberculosis isolates.
Microbiology

Microbiology

Mycobacterial Diseases

Author(s): Prammananan T, Arjratanakool W, Chaiprasert A, Tingtoy N, Leechawengwong M,

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Abstract The emergence of multidrug-resistant tuberculosis (MDR-TB) is increasing and is exacerbated by the human immunodeficiency virus (HIV) epidemic. The standard short-course regimen used for the treatment of tuberculosis is likely to be ineffective against MDR-TB, leading to the need for second-line drugs. In such situations, drug susceptibility testing (DST) is necessary to select an appropriate treatment regimen. In this study, DST of 99 MDR-TB strains isolated in Thailand was performed using a drug-impregnated disc method. The results showed that 94.95\% of the strains were susceptible to amikacin and kanamycin, 90.91\% to ciprofloxacin and ofloxacin, 85.86\% to para-aminosalicylic acid, and 78.79\% to ethionamide.
This article was published in Int J Tuberc Lung Dis and referenced in Mycobacterial Diseases

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