Author(s): PerezRuiz T, MartnezLozano C, Sanz A, Bravo E
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Abstract A sensitive and rapid capillary electrophoretic method combined with laser-induced fluorescence detection has been developed for the determination of ambroxol. Samples were derivatized with 5 x 10(-4) M fluorescein isothiocyanate. A linear relationship between concentration and peak area was obtained in the concentration range 0.008-42 microg ml(-1) with a correlation coefficient of 0.9999. The applicability of the method to serum and urine samples was demonstrated. The method is also useful for the determination of ambroxol in pharmaceutical preparations.
This article was published in J Chromatogr B Biomed Sci Appl
and referenced in Pharmaceutica Analytica Acta