alexa [Serious bacterial keratitis: a retrospective clinical and microbiological study].
Ophthalmology

Ophthalmology

Journal of Clinical & Experimental Ophthalmology

Author(s): Kerautret J, Raobela L, Colin J

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Abstract AIM: To define clinical and microbiological characteristics of patients with bacterial keratitis hospitalized in the Bordeaux University Hospital Department of Ophthalmology. METHODS: A retrospective study of patients presenting serious bacterial keratitis was conducted over 32 months. Clinical features (age, risk factors, description, and visual acuity), progression, and bacteriological characteristics were statistically analyzed. RESULTS: Seventy-three patients were hospitalized from January 2000 to August 2003. The mean age was 43.6 years old. The mean delay for referral was 6 days. Risk factors were noted in 93.1\% of cases: contact lens wear (50\% of risk factors); keratopathy (25\%); corneal trauma (8.8\%); general disease (8.8\%); and corneal surgery (7.3\%). Bacteriological cultures of corneal smears isolated an organism in 57.7\% of cases. Pseudomonas aeruginosa (29.2\%) and coagulase-negative Staphylococcus (22.9\%) were the most frequent species. Gram-negative bacilli and Gram-positive cocci were also present. Gram-negative bacilli were largely dominant when associated with contact lenses (59.3\% of bacteria in contact lens-related keratitis). Visual outcome was significantly correlated with anterior chamber inflammation and initial poor visual acuity. DISCUSSION: In this study, Gram-negative bacilli keratitis appeared to be clearly dominant in cases of contact lens wear. This fact is complementary to the increase in Gram-positive cocci in developed countries, even with contact lens wear.
This article was published in J Fr Ophtalmol and referenced in Journal of Clinical & Experimental Ophthalmology

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