alexa Serological cross-reactivity among Sporothrix schenckii, Ceratocystis, Europhium, and Graphium species.


Journal of Clinical & Experimental Dermatology Research

Author(s): Ishizaki H, Wheat RW, Kiel DP, Conant NF

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Abstract Ethanol-precipitable culture filtrate antigens of 100 strains of 75 species of the Sporothrix-Ceratocystis-Europhium-Graphium complex and 1 species of Botrytis were examined for neutral sugar components and for serological cross-reactivity with S. schenckii rabbit antiserum and human sporotrichosis sera by capillary precipitin and double immunodiffusion assay. Results revealed that cross-reactive species (60 of 77, ca. 80\%) produced exoconidial forms and rhamnose- and mannose-containing polysaccharides and included Ceratocystis, the three known Europhium, and several Graphium-form species. Endoconidial-form Ceratocystis species did not cross-react.
This article was published in Infect Immun and referenced in Journal of Clinical & Experimental Dermatology Research

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