Author(s): Hamdan HZ, Abdelbagi IE, Nasser NM, Adam I
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Abstract BACKGROUND: Maternal cytomegalovirus (CMV) and rubella infections have adverse neonatal outcomes. Basic epidemiological data concerning CMV and rubella is necessary for health planners and care providers. METHODS: A cross sectional study was conducted at El-Rahad hospital, Sudan to investigate seroprevalence of CMV and rubella infections and associated possible risk factors among pregnant women. Structured questionnaires were used to gather socio-demographic data and ELISA was used to detect CMV and rubella infections using IgG and IgM. RESULTS: Out of 231 pregnant women, 167 (72.2\%) and 151 (65.3\%) were CMV-IgG and rubella-IgG positive, respectively. Only 6 (2.5\%) and 8 women (3.4\%) were CMV-IgM and rubella-IgM positive, respectively. While, high parity (OR = 14.7, 95\%CI = 1.7 - 123.6; P = 0.01] and illiteracy (OR = 3.0, CI = 1.4 - 6.5; P = 0.004) were significantly associated with seropostive CMV-IgG in multivariate analysis, none of the other obstetrical and medical characteristics were significantly associated with CMV or rubella infections. CONCLUSION: CMV prevalence was 72.2\% and rubella susceptibility among pregnant women was 34.6\%. Rubella vaccine and routine screening for rubella and CMV should be introduced for pregnant women in this setting. Further research is needed.
This article was published in Virol J
and referenced in Journal of Infectious Diseases & Therapy