Author(s): Patel BN, Mackness MI, Harty DW, Arrol S, BootHandford RP,
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Abstract The levels of activity of four serum esterases were measured in control and streptozotocin-diabetic rats for a period of 6 months. Pseudocholinesterase activity was significantly elevated in the diabetic rats at all time points tested, reaching 250\% of the control activity at 6 months. Levels of paraoxonase activity progressively decreased with time in the diabetic rats, being 36\% lower than in controls at 6 months. No significant differences in either serum arylesterase or carboxylesterase activity between control and diabetic rats were observed.
This article was published in Biochim Biophys Acta
and referenced in Journal of Diabetes & Metabolism