Author(s): Rcker G, Schenkel EP, Manns D, Mayer R, Heiden K,
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Abstract Two bisabolane-type sesquiterpenes, zingiberene-3,6-beta-endoperoxide (1) and zingiberene-3,6-alpha-endoperoxide (2) have been isolated from the aerial parts of Senecio selloi and Eupatorium rufescens. Their structures were determined by spectroscopic methods. Both compounds show schizonticidal activity against Plasmodium falciparum (EC50 = 10 microg/ml).
This article was published in Planta Med
and referenced in Journal of Molecular and Genetic Medicine