alexa Sesquiterpene peroxides from Senecio selloi and Eupatorium rufescens.
Genetics & Molecular Biology

Genetics & Molecular Biology

Journal of Molecular and Genetic Medicine

Author(s): Rcker G, Schenkel EP, Manns D, Mayer R, Heiden K,

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Abstract Two bisabolane-type sesquiterpenes, zingiberene-3,6-beta-endoperoxide (1) and zingiberene-3,6-alpha-endoperoxide (2) have been isolated from the aerial parts of Senecio selloi and Eupatorium rufescens. Their structures were determined by spectroscopic methods. Both compounds show schizonticidal activity against Plasmodium falciparum (EC50 = 10 microg/ml). This article was published in Planta Med and referenced in Journal of Molecular and Genetic Medicine

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