Author(s): Pierce KL, Premont RT, Lefkowitz RJ
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Abstract Seven-transmembrane receptors, which constitute the largest, most ubiquitous and most versatile family of membrane receptors, are also the most common target of therapeutic drugs. Recent findings indicate that the classical models of G-protein coupling and activation of second-messenger-generating enzymes do not fully explain their remarkably diverse biological actions.
This article was published in Nat Rev Mol Cell Biol
and referenced in Journal of Anesthesia & Clinical Research