Author(s): Riedel F, von Stockhausen HB
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Abstract Accidental intoxication with tramadol of a 6-month old infant was followed by severe cerebral depression. Studies on serum, cerebrospinal fluid, and urine drug levels indicated complete penetration of the blood-cerebrospinal fluid barrier by tramadol.
This article was published in Eur J Clin Pharmacol
and referenced in Journal of Clinical Case Reports