alexa Severe hepatic side effects of ezetimibe.
Toxicology

Toxicology

Journal of Clinical Toxicology

Author(s): Stolk MF, Becx MC, Kuypers KC, Seldenrijk CA

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Abstract BACKGROUND AND AIMS: Ezetimibe was introduced recently as a new class of cholesterol-lowering drugs. Until now only limited increases of transaminase levels were reported. METHODS: We studied 2 patients with severe hepatic side effects of ezetimibe in a general community hospital. RESULTS: Ezetimibe may lead to 2 distinct types of severe hepatic side effects. CONCLUSIONS: Ezetimibe may rarely cause hepatotoxicity, severe cholestatic hepatitis, or acute autoimmune hepatitis. This article was published in Clin Gastroenterol Hepatol and referenced in Journal of Clinical Toxicology

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