alexa Severe hypoglycemia during intensive insulin therapy.
Genetics & Molecular Biology

Genetics & Molecular Biology

Journal of Stem Cell Research & Therapy

Author(s): Kaukonen KM, Rantala M, Pettil V, Hynninen M

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Abstract BACKGROUND: Tight glycemic control reduces mortality in surgical intensive care patients and in long-term medical intensive care patients. A large study on intensive insulin therapy was prematurely discontinued due to safety issues. As the safety of intensive insulin therapy has been questioned, we screened all patients during a 17-month period to reveal the incidence of hypoglycemia and its effects on the outcome of the patients. METHODS: All patients treated between February 2005 and June 2006 in two intensive care units (ICUs) of a tertiary care teaching hospital were included in the study. A nurse-driven intensive insulin therapy with a target blood glucose level of 4-6 mmol/l had been introduced earlier. The patients were divided into two groups according to the presence of severe hypoglycemia (
  • DOI: 10.1111/j.1399-6576.2008.01795.x
  • This article was published in Acta Anaesthesiol Scand and referenced in Journal of Stem Cell Research & Therapy

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