alexa Severe malaria in children: A descriptive report from Kinshasa, the Democratic Republic of Congo.
Infectious Diseases

Infectious Diseases

Malaria Control & Elimination

Author(s): Kunuanunua TS, Nsibu CN, Bodi JM, Tshibola TK, Makusi Bura M,

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Abstract The decline of susceptibility of Plasmodium falciparum to chloroquine and sulfadoxine-pyrimethamine resulted in the change of drug policy. This policy has probably changed the facies of the severe form of malaria. A prospective study was conducted in Kinshasa, the Democratic Republic of Congo. Data on children aged ≤13 years, diagnosed with severe malaria were analyzed. In total, 378 children were included with an overall median age of 8 years (age range: 1-13 years). Dark urine was seen in 25.1\% of cases. Metabolic acidosis (85.2\%), hypoglycemia (62.2\%) and hemoglobin ≤5 g/dl (39.1\%) were the common laboratories features. Severe malaria anemia, cerebral malaria and Blackwater fever (BWF) were found in 39.1, 30.1 and 25.4\%, respectively. Mortality rate was 4\%. BWF emerges as a frequent form of severe malaria in our midst. Availing artemisin-based combination treatments in the health care system is a priority to reduce the incidence of BWF in our environment. © The Author [2015]. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com. This article was published in J Trop Pediatr and referenced in Malaria Control & Elimination

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