alexa Shedding "UV" light on endogenous opioid dependence.


Journal of Clinical & Experimental Dermatology Research

Author(s): Tejeda HA, Bonci A, Tejeda HA, Bonci A

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Abstract Excessive sun tanning can result in addictive behavior. In this issue of Cell, Fell et al. utilize a combination of behavioral pharmacology and transgenic mice to demonstrate that chronic UV light exposure recruits p53 signaling in keratinocytes, subsequently increasing β-endorphin signaling at opioid receptors, and produces an endogenous opioid-dependent state. Copyright © 2014 Elsevier Inc. All rights reserved. This article was published in Cell and referenced in Journal of Clinical & Experimental Dermatology Research

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