Author(s): Hamdouchi C, Ezquerra J, Vega JA, Vaquero JJ, AlvarezBuilla J,
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Abstract Various 2-amino-3-acyl-6-[(E)-1-phenyl-2-N-methylcarbamoylvinyl]-imidazo[1 ,2-a]pyridines, structurally related to Enviroxime were prepared to determine the effect of acyl groups on the anti-rhinoviral activity. A short and efficient means for the construction of the imidazo nucleus as well as biological evaluation of the final compounds are disclosed.
This article was published in Bioorg Med Chem Lett
and referenced in Medicinal Chemistry