Author(s): Brivanlou AH, Darnell JE Jr
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Abstract More than 2000 transcription factors are encoded in the human genome. Such proteins have often been classified according to common structural elements. But because transcription factors evolved in the service of biologic function, we propose an alternative grouping of eukaryotic transcription factors on the basis of characteristics that describe their roles within cellular regulatory circuits.
This article was published in Science
and referenced in Journal of Clinical & Cellular Immunology