Author(s): Fleming ID, Barnawell JR, Burlison PE, Rankin JS
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Abstract Skin cancer is rare in black patients. The clinical course and pathology of 58 cases are presented and reviewed. These include 38 squamous cell carcinomas, 13 malignant melanomas, and 7 basal cell carcinomas. Sixty-one percent of the squamous cell carcinomas developed in unexposed areas, with sunlight exposure apparently not being an important etiologic factor. Forty-one percent of the squamous cell carcinomas had predisposing factors such as burn scars or chronic infection. Squamous cell carcinoma in black patients is an aggressive disease, with 29\% developing regional lymph node metastasis, and a mortality of 29\%. Malignant melanomas occurred most frequently on the plantar surface of the foot (76\%). Melanoma is also a virulent tumor in black patients, with 11 of 13 patients developing lymph node metastasis and only 2 patients surviving. Skin cancer in black patients presents a very different clinical picture than that seen in white patients. It is important that these factors be considered when planning therapy.
This article was published in Cancer
and referenced in Dermatology and Dermatologic Diseases
- Hana Zelenkova
Therapy with immune modulators (cyclosporine A) in dermatology (focusing on psoriasis, atopic eczema, allergic vasculitis, and chronic urticaria)
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