Author(s): Choo EK, Magruder W, Montgomery CJ, Lim J, Brant R,
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Abstract BACKGROUND: The number of fluctuations of skin conductance per second (NFSC) has been shown to correlate with induced pain and self-report pain scales. This study aimed to evaluate the validity and feasibility of NFSC as an objective measurement of nociception intensity in school-aged children after surgery. METHODS: After approval by the research ethics board and obtaining consent, 100 subjects participated in this prospective observational study. Preoperatively, NFSC was measured for 60 s at rest and during response to a self-report pain scale (numeric rating scale [NRS], Faces Pain Scale-Revised) and anxiety scoring (NRS). Postoperative measurements were repeated every 10 min for 30 min or until NRS pain score was or= 7) with 56.3\% sensitivity (95\% CI = 37.7-73.6\%) and 78.4\% specificity (95\% CI = 71.7-84.1\%). The area under receiver operator characteristic curve for NFSC was 69.1\%. CONCLUSIONS: NFSC measurement is feasible in a perioperative setting but was not specific for postoperative pain intensity and was unable to identify analgesia requirements when compared with self-report measures.
This article was published in Anesthesiology and referenced in Pediatrics & Therapeutics