alexa Snapshots: chromatin control of viral infection.
Immunology

Immunology

Immunotherapy: Open Access

Author(s): Knipe DM, Lieberman PM, Jung JU, McBride AA, Morris KV, , Knipe DM, Lieberman PM, Jung JU, McBride AA, Morris KV, , Knipe DM, Lieberman PM, Jung JU, McBride AA, Morris KV, , Knipe DM, Lieberman PM, Jung JU, McBride AA, Morris KV,

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Abstract Like their cellular host counterparts, many invading viral pathogens must contend with, modulate, and utilize the host cell's chromatin machinery to promote efficient lytic infection or control persistent-latent states. While not intended to be comprehensive, this review represents a compilation of conceptual snapshots of the dynamic interplay of viruses with the chromatin environment. Contributions focus on chromatin dynamics during infection, viral circumvention of cellular chromatin repression, chromatin organization of large DNA viruses, tethering and persistence, viral interactions with cellular chromatin modulation machinery, and control of viral latency-reactivation cycles. Published by Elsevier Inc.
This article was published in Virology and referenced in Immunotherapy: Open Access

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