alexa Social consequences of multiple sclerosis. Part 2. Divorce and separation: a historical prospective cohort study.
Neurology

Neurology

Journal of Multiple Sclerosis

Author(s): Pfleger CC, Flachs EM, KochHenriksen N

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Abstract BACKGROUND: There is a need for follow-up studies of the familial situation of multiple sclerosis (MS) patients. OBJECTIVES: To evaluate the probability of MS patients to remain in marriage or relationship with the same partner after onset of MS in comparison with the population. PATIENTS AND METHODS: All 2538 Danes with onset of MS 1980-1989, retrieved from the Danish MS-Registry, and 50,760 matched and randomly drawn control persons were included. Information on family status was retrieved from Statistics Denmark. Cox analyses were used with onset as starting point. RESULTS: Five years after onset, the cumulative probability of remaining in the same relationship was 86\% in patients vs. 89\% in controls. The probabilities continued to deviate, and at 24 years, the probability was 33\% in patients vs. 53\% in the control persons (p < 0.001). Among patients with young onset (< 36 years of age), those with no children had a higher risk of divorce than those having children less than 7 years (Hazard Ratio 1.51; p < 0.0001), and men had a higher risk of divorce than women (Hazard Ratio 1.33; p < 0.01). CONCLUSION: MS significantly affects the probability of remaining in the same relationship compared with the background population. This article was published in Mult Scler and referenced in Journal of Multiple Sclerosis

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