alexa Sonoporation, anti-cancer drug and antibody delivery using ultrasound.
Materials Science

Materials Science

Journal of Nanomedicine & Nanotechnology

Author(s): Wu J, Pepe J, Rincn M

Abstract Share this page

Abstract It has been shown experimentally in cell suspensions that sonoporation could be used to deliver the anti-cancer drug Adriamycin hydrochloride (ADR) into Jurkat lymphocytes and that it could also be used to deliver goat anti-rabbit IgG and anti-mouse IgD, antibodies into human peripheral blood mononuclear cells (PBMC) and Jurkat lymphocytes. When ADR was delivered, the delivery efficiency reached 4.80+/-2.04\% and control baseline (no ultrasound and no ADR) was 0.17+/-0.14\%. When anti-rabbit IgD was delivered, the efficiencies were 34.90+/-1.80\% (control baseline was 1.33+/-0.31\%) and 32.50+/-4.36\% (control baseline was 1.66+/-0.06\%) respectively for Jurkat cells and PBMC. When goat anti-rabbit IgG was delivered, the efficiencies were 78.60+/-3.60\% (control baseline was 1.60+/-0.00\%) and 57.50+/-4.23\% (control baseline was 11.30+/-0.81\%) respectively for Jurkat cells and PBMC. This article was published in Ultrasonics and referenced in Journal of Nanomedicine & Nanotechnology

Recommended Conferences

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords