Author(s): Damiani PC, Bearzotti M, Cabezn MA
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Abstract The spectrofluorometric determination of ibuprofen in pharmaceutical tablets, creams and syrup is described. It involves excitation at 263 nm and emission at 288 nm. the linear range is 2-73 mg L(-1). Other drugs or excipients present in the different formulations do not interfere, except in the case of chlorzoxazone containing tablets. Due to its strong absorbance in the spectral range the chlorzoxazone does interfere, so that in this case the proposed method can't be applied.
This article was published in J Pharm Biomed Anal
and referenced in Journal of Bioanalysis & Biomedicine