alexa Sphingolipids as therapeutics.
Chemical Engineering

Chemical Engineering

Journal of Analytical & Bioanalytical Techniques

Author(s): Kester M, Kolesnick R

Abstract Share this page

Abstract The sphingolipid field has made significant strides over the past 10 years: from identifying metabolites of the sphingomyelin pathway as second messengers to discerning the molecular biology and biophysics of these lipid-derived second messengers. Building upon this vast basic science literature, scientists from multiple disciplines have begun to translate manipulations of endogenous sphingolipid metabolites and targets into therapeutic initiatives. Multiple publications have reviewed the biochemistry [Biochemistry 40 (16) (2001) 4893 [1]; Environ. Health Perspect. 109 (Suppl. 2) (2001) 283 ], biophysics [J. Cell Physiol. 184 (3) (2000) 285; Trends Cell Biol. 10 (10) (2000) 408 ], molecular biology [Biochim. Biophys. Acta 1426 (2) (1999) 347 ], and physiology [J. Biol. Chem. 277 (29) (2002) 25851; J. Biol. Chem. 277 (29) (2002) 25847 ] of sphingolipid metabolites. The present review serves to document the emerging concept of sphingolipid metabolites as therapeutics with clear clinical potential.
This article was published in Pharmacol Res and referenced in Journal of Analytical & Bioanalytical Techniques

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords