alexa Spike detection using the continuous wavelet transform.
Mathematics

Mathematics

Journal of Applied & Computational Mathematics

Author(s): Nenadic Z, Burdick JW, Nenadic Z, Burdick JW

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Abstract This paper combines wavelet transforms with basic detection theory to develop a new unsupervised method for robustly detecting and localizing spikes in noisy neural recordings. The method does not require the construction of templates, or the supervised setting of thresholds. We present extensive Monte Carlo simulations, based on actual extracellular recordings, to show that this technique surpasses other commonly used methods in a wide variety of recording conditions. We further demonstrate that falsely detected spikes corresponding to our method resemble actual spikes more than the false positives of other techniques such as amplitude thresholding. Moreover, the simplicity of the method allows for nearly real-time execution. This article was published in IEEE Trans Biomed Eng and referenced in Journal of Applied & Computational Mathematics

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