alexa Statin therapy is associated with improved survival in ischemic and non-ischemic heart failure.


Journal of Clinical & Experimental Cardiology

Author(s): Horwich TB, MacLellan WR, Fonarow GC

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Abstract OBJECTIVES: This study aimed to investigate the impact of hydroxymethylglutaryl coenzyme A reductase inhibitor (statin) therapy in patients with advanced heart failure (HF). BACKGROUND: Although statins are known to reduce mortality in coronary artery disease (CAD), the impact of statin therapy in patients with HF has not been well studied. Both the potential risks and benefits of statins in HF have been described. METHODS: We studied a cohort of 551 patients with systolic HF (left ventricular ejection fraction [EF]
  • DOI: 10.1016/j.jacc.2003.07.049
  • This article was published in J Am Coll Cardiol and referenced in Journal of Clinical & Experimental Cardiology

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