alexa Statin-associated myasthenia gravis: report of 4 cases and review of the literature.


Journal of Neurology & Neurophysiology

Author(s): Purvin V, Kawasaki A, Smith KH, Kesler A

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Abstract A few recent individual case reports have suggested that a myasthenic syndrome may be associated with statin treatment, but this association is not well described. We report 4 patients who developed symptoms of myasthenia gravis within 2 weeks of starting treatment with a statin drug. In 1 case the drug appears to have exacerbated underlying myasthenic weakness, whereas in the other 3 cases, de novo antibody formation appears to be most likely. In each case, some degree of recovery followed discontinuation of the statin medication. This article was published in Medicine (Baltimore) and referenced in Journal of Neurology & Neurophysiology

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