alexa Statins--a cure-all for the brain?
Immunology

Immunology

Journal of Clinical & Cellular Immunology

Author(s): Menge T, Hartung HP, Stve O

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Abstract 'Statins' are 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors - oral cholesterol-lowering drugs that are used to treat hypercholesterolaemia. It is widely accepted that statins have anti-inflammatory effects that are independent of their ability to lower cholesterol. Animal studies and observational clinical studies have indicated that statins might also be effective in treating certain neurological diseases - in particular, multiple sclerosis, Alzheimer's disease and ischaemic stroke. At present, however, results from ongoing prospective, randomized clinical trials are not available. This article was published in Nat Rev Neurosci and referenced in Journal of Clinical & Cellular Immunology

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