alexa Stem-cell niches: nursery rhymes across kingdoms.
Dermatology

Dermatology

Hair Therapy & Transplantation

Author(s): Scheres B

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Abstract Despite the large evolutionary distance between the plant and animal kingdoms, stem cells in both reside in specialized cellular contexts called stem-cell niches. Although stem-cell-specification factors have been recruited from plant-specific gene families, maintenance factors that repress stem-cell differentiation are conserved between plants and animals. Recent evidence indicates that stem cells in multicellular organisms can be specified by kingdom-specific patterning mechanisms that connect to a related core of epigenetic stem-cell factors. This article was published in Nat Rev Mol Cell Biol and referenced in Hair Therapy & Transplantation

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