alexa Stimulation of the yeast mitochondrial calcium uniporter by hypotonicity and by ruthenium red.


Biochemistry & Analytical Biochemistry

Author(s): Bazhenova EN, Saris NE, Zvyagilskaya RA

Abstract Share this page

Abstract The Ca2+ uptake by mitochondria from the yeast Endomyces magnusii has earlier been found to be driven by the membrane potential and to be stimulated by spermine. It thus functions in a similar fashion as the animal mitochondrial calcium uniporter. Here, it is shown that the uptake is stimulated, i.e., Ca2+ can be accumulated from lower [Ca2+], under hypotonic conditions. Ruthenium Red, an inhibitor of the animal uniporter, under certain conditions, stimulates the yeast uniporter. The mechanism of the stimulation by hypotonicity and Ruthenium Red is discussed. Copyright 1998 Elsevier Science B.V.
This article was published in Biochim Biophys Acta and referenced in Biochemistry & Analytical Biochemistry

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Relevant Topics

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version