alexa Striatal function in generalized social phobia: a functional magnetic resonance imaging study.
Psychiatry

Psychiatry

Journal of Child and Adolescent Behavior

Author(s): Sareen J, Campbell DW, Leslie WD, Malisza KL, Stein MB, Paulus MP, Paulus MP, Kjernisted KD, Walker JR, Reiss JP

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Although evidence suggests the involvement of the amygdala in generalized social phobia (GSP), few studies have examined other neural regions. Clinical, preclinical, and dopamine receptor imaging studies demonstrating altered dopaminergic functioning in GSP suggest an association with striatal dysfunction. This is the first functional magnetic resonance imaging (fMRI) study to use a cognitive task known to involve the striatum to examine the neural correlates of GSP. We examined whether subjects with GSP had differential activation in striatal regions compared with healthy control subjects while engaged in a cognitive task that has been shown to activate striatal regions reliably.

This article was published in Biol Psychiatry and referenced in Journal of Child and Adolescent Behavior

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