alexa Structure, sequence and expression of the hepatitis delta (delta) viral genome
Infectious Diseases

Infectious Diseases

Journal of Infectious Diseases & Therapy

Author(s): KANGSHENG WANG, QUILIM CHOO, AMY J WEINER, JINGHSIUNG OU, RICHARD C NAJARIAN

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Biochemical and electron microscopic data indicate that the human hepatitis delta viral agent contains a covalently closed circular and single-stranded RNA genome that has certain similarities with viroid-like agents from plants. The sequence of the viral genome (1,678 nucleotides) has been determined and an open reading frame within the complementary strand has been shown to encode an antigen that binds specifically to antisera from patients with chronic hepatitis delta viral infections.

This article was published in Nature and referenced in Journal of Infectious Diseases & Therapy

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