Author(s): Kuldip Singh, Ramandeep Kaur, Arvind Preet Kaur
Reactive oxygen species are generated in cells under normal metabolic activities are implicated in several metabolic diseases that include heart diseases, acquired immunodeficiency syndrome, diabetes mellitus, arthritis, cancer, aging, liver disorder etc. The antioxidant therapy has gained an utmost importance in the treatment of these metabolic diseases. The World Health Organization in 2006 estimated that 4 billion people use herbal medicines in some aspects of primary healthcare and there is a growing tendency to “Go Natural”. In these aspects, all around the world, the medicinal properties of plants have been investigated and explored for their potential antioxidant activities to counteract metabolic disorders, which are of high economically viable, with no side effects. The present study was designed to explore the antioxidant and antimicrobial potential by measuring antioxidant activity and antimicrobial activity in Syzygium cumini leaves extracts. The healthy plants were collected from the fields of Chunni Kalan Distt. Fatehgarh Sahib (Punjab)- India for the determination of antioxidant activity. The four strains of bacteria like Escherichia coli, Salmonella typhi, Pseudomonas aeruginosa & Staphylococcus aureus and two fungus such as spergillks niger & Trichoderma viru were used to measure the antimicrobial & antifungal activity of Syzygium cumini. The aqueous, ethanol and Ethyl Acetate extracts of Syzygium cumini leaves were prepared for the determination of total phenolic ascorbic acid, hydrogen peroxide scavenging activity & antioxidant activity and antimicrobial activity. A high contents of Phenolic Content, Hydrogen Peroxide Scavenging activity, Antioxidant Activity and Vitamin-C were observed in various leaves extracts (aqueous, alcohol and ethyl acetate) of Syzygium cumini were recorded. The antibacterial and antifungal activities were also observed in different extracts of by means of Syzygium cumini. All the above observations suggested that Syzygium cumini leaves have antioxidant and Antimicrobial activity.