alexa [Study on antioxidative activities of Psidium guajava Linn leaves extracts].
Pharmaceutical Sciences

Pharmaceutical Sciences

Medicinal & Aromatic Plants

Author(s): Wang B, Jiao S, Liu H, Hong J

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Abstract OBJECTIVE: To study the antioxidative activities of the extracts from Psidium guajava Linn leaves (PGL). METHODS: The PGL was submersed with distilled water, 65\% ethanol and 95\% ethanol respectively. The 3 extracts were obtained after the solutions were filtered, concentrated and dried. The scavenging rate to hydroxyl radicals and inhibiting rate to lipid peroxidation were analyzed for the 3 extracts. Their contents of total flavonoids were determined by ultraviolet spectrophotometry, and the components of total flavonoids were primarily identified by high performance liquid chromatography (HPLC) and ultraviolet-visible absorption spectrometry (UV). RESULTS: The extracts from distilled water, 65\% ethanol and 95\% ethanol respectively showed effects on scavenging hydroxyl radicals and inhibiting lipid peroxidation in the dose-dependent manner, had 50\% effective concentration (EC50) on scavenging hydroxyl radicals of 0.63, 0.47 and 0.58g/L, had EC50 on inhibiting lipid peroxidation of 0.20, 0.035, 0.18g/L and had total flavonoids contents of 3.28, 30.71 and 55.98g/kg respectively. CONCLUSION: The aquatic and the ethanol extracts from PGL possess the potential antioxidative activities in the study. The flavonoids may be one of their antioxidative components.
This article was published in Wei Sheng Yan Jiu and referenced in Medicinal & Aromatic Plants

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