Author(s): Yashima E, Tajima T, Suehiro N, Akashi M, Miyauchi N
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Abstract The interaction of several aromatic cationic dyes such as, ethidium bromide (EB), methylene blue (MB), acridine orange (AO), and Hoechst 33258 with calf-thymus DNA and poly(A)-poly(U) duplex was investigated. The different induced extrinsic Cotton effects (greater than 300 nm) were observed for DNA- and RNA-dye complexes. The binding properties of these complexes were examined by UV, CD, and NMR spectroscopies.
This article was published in Nucleic Acids Symp Ser
and referenced in Journal of Medical Microbiology & Diagnosis