Author(s): Heineck I, Bueno D, Heydrich J
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Abstract OBJECTIVE: To describe the use of drugs in patients using Enteral Feeding Tubes (EFT) at a University Hospital in southern Brazil. METHOD: A total of 315 medical charts of patients that had used EFT were analyzed. Variables of interest were: days the tube was used, number and frequency of drugs administered by the tube, pharmaceutical dosage forms and the number of tube exchanges per patients. RESULTS: The mean of age of the patients was 59 years (SD = 21) and 59\% were male. A mean number of drugs prescribed per patient with tube administration were five. Almost all patients (95\%) used some drugs in solid pharmaceutical preparations, mostly tablets (72\%). About 158 different drugs were prescribed; for 23\% of these, the prescription of liquid dosage forms was possible. The chance of changing the enteral tube was greater for patients that used more than five drugs enterally (OR = 4.8, 95\% CI 2.8-8.2) and that had more than 13 drug administrations per day (OR = 5.3, 95\% CI 3.1-9.3). CONCLUSION: This study provides evidence that patients using more drugs enterally have a greater chance of having their enteral tube exchanged. Furthermore, it suggests a lack of knowledge of the health team with regard to the appropriateness of pharmaceutical preparations for this administration.
This article was published in Pharm World Sci
and referenced in Biochemistry & Analytical Biochemistry