alexa Successful lung transplantation for talcosis secondary to intravenous abuse of oral drug.


Journal of Vascular Medicine & Surgery

Author(s): Shlomi D, Shitrit D, Bendayan D, Sahar G, Shechtman Y,

Abstract Share this page

Abstract Talcosis due to intravenous injection of oral drugs can cause severe pulmonary disease with progressive dyspnea even when drug use is discontinued. We describe a 54-year-old woman with severe emphysema who underwent left lung transplantation. The patient had a remote history of intravenous injection of crushed methylphenidate (Ritalin) tablets. Chest computed tomography showed severe emphysematous changes, more prominent in the lower lobes. Microscopic examination of the extracted lung demonstrated multinucleated giant cells with birefringent crystals, compatible with talcosis. At follow-up, daily symptoms were completely alleviated and lung function was good. We recommend that lung transplantation be considered as a viable option in the treatment of talcosis.
This article was published in Int J Chron Obstruct Pulmon Dis and referenced in Journal of Vascular Medicine & Surgery

Relevant Expert PPTs

Relevant Speaker PPTs

  • Khalil Khanafer
    PPT Version | PDF Version
  • Ishfaq A Bukhari
    Protective Effect of Diltiazem and Fenofibrate Against Ischemia-reperfusion Induced Cardiac Arrhythmias in the Isolated Rat Heart.
    PPT Version | PDF Version
  • Zamaneh Kassiri
    Loss of tissue inhibitor of metalloproteinase-3 (Timp3) leads to abdominal aortic aneurysm (AAA)
    PDF Version
  • Fulvia Seccareccia
    Transcatheter aortic valve implantation versus surgical aortic valve replacement for severe aortic stenosis: Results from an intermediate risk propensity-matched population of the Italian OBSERVANT Study
    PDF Version
  • Janardhana Rao Babburi
    An unusual case of LV Myxoma extending through Aortic Valve presented with Antero Septal Myocardial Infarction
    PDF Version

Recommended Conferences

  • 19th Annual Cardiology Conference (10 Plenary Forums - 1 Event)
    August 31-September 01, 2017 Philadelphia, USA

Relevant Topics

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version