Author(s): Mohteshamzadeh M, Coutinho A, Erekosima I, Rustom R, Wong CF
BACKGROUND: A female with autosomal dominant polycystic kidney disease was followed up over the course of four pregnancies. Her first three pregnancies were unsuccessful. Her fourth pregnancy resulted in a live birth, but at what expense?
INVESTIGATIONS: The diagnosis of autosomal dominant polycystic kidney disease was confirmed by ultrasound imaging. Physical examination, blood pressure measurement, and urine and blood analyses were performed at each follow-up visit.
DIAGNOSIS: Deterioration of renal function following multiple complicated pregnancies.
MANAGEMENT: Attention to blood pressure and proteinuria delayed initiation of dialysis, but effects of the number of pregnancies took their toll. The patient was started on hemodialysis and underwent renal transplantation.Gynecology & Obstetrics