alexa Swedish Two-County Trial: Impact of Mammographic Screening on Breast Cancer Mortality during 3 Decades


Advances in Cancer Prevention

Author(s): Lszl Tabr

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The Swedish Two-County Trial of mammographic screening was the first breast screening trial to show a reduction in breast cancer mortality from screening with mammography alone, finding a 30% reduction in breast cancer mortality among 40–74-year-old women invited to screening (1). Regular updates of the trial data have shown that the relative effect of invitation to screening on breast cancer mortality has remained stable over extensive follow-up (2–4). The absolute benefit in terms of lives saved, however, has increased with longer follow-up times (2,5,6). Because breast screening prevents deaths in the medium to long term, rather than in the immediate future, long-term follow-up (at least 15 years) is required to estimate the absolute number of breast cancer deaths prevented (6).

This article was published in Radiology and referenced in Advances in Cancer Prevention

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