Author(s): Amoros M, Simes CM, Girre L, Sauvager F, Cormier M, Amoros M, Simes CM, Girre L, Sauvager F, Cormier M
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Abstract The in vitro activity against herpes simplex virus type 1 of the major flavonoids identified in propolis was investigated. Flavonols were found to be more active than flavones, the order of importance being galangin, kaempferol, and quercetin. The efficacy against HSV-1 of binary flavone-flavonol combinations has been also investigated. The synergy demonstrated by all combinations could explain why propolis is more active than its individual compounds.
This article was published in J Nat Prod
and referenced in Journal of Clinical & Experimental Pharmacology