Author(s): Suda M, Katoh M, Toda K, Matsumoto K, Kawaguchi K,
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Abstract Synthesis of procyanidin B2 and B3 gallate derivatives, 3-O-gallate, 3"-O-gallate, and 3,3"-di-O-gallate, were synthesized using equimolar condensation mediated by Yb(OTf)3. Synthesized compounds showed significant antitumor effects against human prostate PC-3 cell lines. Their activities were weaker than well-known EGCG and prodelphinidin B3. Copyright © 2013 Elsevier Ltd. All rights reserved.
This article was published in Bioorg Med Chem Lett
and referenced in Organic Chemistry: Current Research