alexa Synthesis and biological evaluation of some new substituted naphthoquinones.

Journal of Autacoids and Hormones

Author(s): Habib NS, Bekhit AA, Park JY

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Abstract Two novel series of 1,4-naphthoquinone derivatives have been synthesized namely; N-ethoxycarbonyl-2-ethoxycarbonyloxy-3- alkyl-1,4-naphthoquinon-1-substituted phenylhydrazones 3a-f and 2-chlorocetyloxy-3-alkyl-1,4-naphthoquinone-1-substituted phenylhydrazones 4a-d. The antimicrobial activity as well as anticancer activity of these compounds have been evaluated. The acute toxicity of the active compounds was determined.
This article was published in Boll Chim Farm and referenced in Journal of Autacoids and Hormones

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