Author(s): Naidu KR, Khalivulla SI, Rasheed S, Fakurazi S, Arulselvan P, , Naidu KR, Khalivulla SI, Rasheed S, Fakurazi S, Arulselvan P,
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Abstract Polymer supported dichlorophosphate (PEG-OPOCl(2)) is an efficient green catalyst for the electrophilic substitution reaction of indole with aromatic aldehydes, in neat condition, to afford an excellent yield of bis(indolyl) methanes with short reaction time, at room temperature. The synthesized compounds and their anti-cancer activity are evaluated.
This article was published in Int J Mol Sci
and referenced in Journal of Drug Metabolism & Toxicology